Locomotor activity in rodents is routinely assessed in the evaluation of
drugs and other behavioural studies. Numerous laboratory equipment can be used
to measure locomotion of rodents. However, the huge cost of the equipment has
posed a great challenge to the Department of Pharmacology of Kwame Nkrumah
University of Science and Technology (KNUST) which has only one Actimeter to
measure locomotor activity of rodents. To overcome this challenge, three
Postgraduate students viz. Elikplim Kwesi Ampofo, Mary Ayeko Twumasi and Victor
Wumbor-Apin Kumbol all from the Faculty of Pharmacy and Pharmaceutical
Sciences, KNUST, have developed a newer model Actimeter.
The Project Team,
from left; Elikplim Kwesi Ampofo, Mary Ayeko Twumasi and Victor
Wumbor-Apin Kumbol
In an
exclusive interview with the team, the students revealed that most postgraduate
students of Pharmacology did not have access to the Actimeter because of the
high demand of usage by other colleagues. They, therefore, came up with the
idea of designing and developing an Actimeter to add up to the one available.
According to Mr. Kumbol, there is
a new movement in Sciences which gives them the opportunity to build their own
laboratory equipment. This opportunity enabled them to participate in the 1st
TReND Advanced Open Lab Ware Workshop and also provided them with funds to
build the Actimeter.
Mr. Kumbol said the Actimeter is
an automated open source for rodents. The design of the hardware consists of 3D
printed and laser-cut parts as well as ‘off-the-self’ electronic components.
Also, the rodent locomotor activity can be recorded using the IR motion
detection system in Actimeter. The team through validation process proved that
the hardware system is comparable to commercial and open source video tracking
systems.
The Actimeter is particularly useful to laboratories in need of a
reliable and inexpensive equipment and can be easily built.
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